The Mouse CD4 Monoclonal Antibody (PE/Cyanine7 Conjugated, GK1.5) is a sophisticated tool for researchers investigating immune responses in mice. This antibody, offered by Assay Genie, is specifically designed to target the CD4 cell surface molecule in murine samples. The GK1.5 antibody is conjugated with PE/Cyanine7, enabling easy visualization and analysis using flow cytometry or fluorescence microscopy techniques.CD4, a critical marker for T-helper cells, plays a pivotal role in coordinating immune responses and regulating adaptive immunity. The GK1.5 antibody allows for precise detection of CD4 expression, allowing researchers to study T-cell activation, differentiation, and function in various experimental setups.
Its high specificity and sensitivity ensure accurate and reliable results, making it an invaluable tool for immunologists, vaccine developers, and researchers studying autoimmune diseases and infectious agents in mouse models.By utilizing the Mouse CD4 Monoclonal Antibody (PE/Cyanine7 Conjugated, GK1.5), scientists can gain valuable insights into the complex mechanisms of immune regulation and T-cell biology in murine systems, paving the way for advancements in immunotherapy, drug development, and disease intervention strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.