The Mouse CD4 Monoclonal Antibody PE-Cyanine5 Conjugated (GK1.5) (AGEL1249) offered by AssayGenie is a high-quality reagent designed for the specific detection of CD4, a key cell surface marker involved in immune responses. This antibody, derived from mouse monoclonal sources and conjugated with PE-Cyanine5, is optimized for flow cytometry applications and excels in identifying CD4-positive cells in various samples.CD4, a critical component of the immune system, is mainly found on T helper cells and plays a pivotal role in orchestrating immune responses by interacting with antigen-presenting cells. The ability of this antibody to target CD4 aids researchers in characterizing immune cell populations, monitoring immune activation, and understanding immune function in health and disease.
Its reliable performance and specificity make it indispensable for immunology studies, infectious disease research, and immunotherapy development efforts.Researchers exploring T cell biology, immune system modulation, and vaccine development will find the Mouse CD4 Monoclonal Antibody PE-Cyanine5 Conjugated (GK1.5) (AGEL1249) from AssayGenie to be a valuable tool for advancing their scientific investigations and gaining insights into the intricate workings of the immune response.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.