The Mouse CD4 Monoclonal Antibody (APC Conjugated) GK1.5 (AGEL1247) from Assay Genie is a valuable tool for research involving CD4, a crucial cell surface marker found on helper T cells. This antibody, specifically designed for flow cytometry applications, is highly reactive with mouse samples and provides reliable detection and analysis of CD4 expression in various cell types.CD4, also known as T-cell surface antigen T4, is essential for the activation of T cells and plays a key role in immune responses. By targeting CD4, researchers can gain insights into T cell function, differentiation, and activation, making this antibody an ideal choice for immunology studies and research on infectious diseases, autoimmune disorders, and immune system dysregulation.
With its high specificity and sensitivity, the Mouse CD4 Monoclonal Antibody (APC Conjugated) GK1.5 (AGEL1247) offers researchers a powerful tool to investigate the role of CD4 in immune regulation and disease pathogenesis, ultimately advancing our understanding of immune responses and potentially leading to the development of new therapeutic strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.