The Mouse CD4 Monoclonal Antibody (APC-conjugated, GK1.5) is a powerful tool for researchers studying immune responses in mouse models. This antibody, labeled with APC for enhanced detection, specifically targets the CD4 protein found on the surface of T-helper cells. By binding to CD4, the antibody allows for precise identification and analysis of these critical immune cells in various experimental settings.CD4 is a key marker for T-helper cells, playing a central role in coordinating immune responses and regulating the activities of other immune cells. The GK1.5 monoclonal antibody provides researchers with a reliable means of tracking CD4-expressing cells in flow cytometry and other immunological assays.
Its use is particularly valuable in studies focusing on T-cell biology, autoimmune diseases, infectious diseases, and immunotherapy research.By utilizing the Mouse CD4 Monoclonal Antibody (APC-conjugated, GK1.5), researchers can gain deeper insights into the functioning of the immune system and the intricate interactions between different immune cell populations. This antibody is an essential tool for advancing our understanding of immune regulation and developing novel therapeutic strategies targeting CD4-positive cells.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.