The Mouse CD4 Monoclonal Antibody (Alexa Fluor 488 Conjugated, GK1.5) is a specialized tool for researchers in immunology, cell biology, and related fields. This antibody, offered by AssayGenie, is specifically designed for the detection and analysis of the CD4 protein, a key cell surface marker involved in immune responses and T-cell activation.The GK1.5 antibody, conjugated with Alexa Fluor 488, provides researchers with a highly sensitive and specific tool for visualizing CD4 expression in various experimental setups. The green fluorescence emitted by Alexa Fluor 488 allows for easy and clear detection of CD4-positive cells in flow cytometry, immunofluorescence, and other fluorescence-based assays.CD4 is a critical protein in the immune system, playing a central role in the activation and function of T-helper cells.
By targeting CD4 with the GK1.5 antibody, researchers can gain valuable insights into immune cell dynamics, T-cell differentiation, and immune responses in health and disease contexts. This antibody is rigorously validated for its specificity and performance, ensuring reliable results in diverse research applications.Overall, the Mouse CD4 Monoclonal Antibody (Alexa Fluor 488 Conjugated, GK1.5) from AssayGenie is a powerful tool for investigating the intricate mechanisms of immune regulation and T-cell biology, ultimately advancing our understanding of immune-mediated diseases and potentially informing the development of novel therapeutic approaches.
Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.