FITC Anti-Mouse CD38 Antibody [NIMR5] (AGEL2013)

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SKU:
AGEL2013
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Mouse CD38 Antibody [NIMR5]

The Mouse CD38 Monoclonal Antibody (FITC Conjugated) NIMR5 (AGEL2013) is a powerful tool for research involving CD38, a transmembrane glycoprotein widely expressed on various cell types, including immune cells and hematopoietic cells. This monoclonal antibody, conjugated with FITC for easy visualization, is specifically designed for fluorescence-based assays.CD38, a multifunctional enzyme involved in cell adhesion, signal transduction, and calcium signaling, is a key player in immune response modulation, inflammation, and cell activation. Its high expression in immune cells like lymphocytes and monocytes makes it a crucial target for studying immune function and diseases related to immune dysregulation, such as autoimmune disorders, infectious diseases, and cancer.

The NIMR5 monoclonal antibody specifically targets CD38, enabling researchers to detect and quantify CD38 expression in different cell populations. This antibody is ideal for flow cytometry applications, allowing for the analysis of CD38 levels in a range of cell types and conditions. By understanding the role of CD38 in immune modulation and disease pathogenesis, researchers can uncover new insights and potential therapeutic targets for various health conditions.

Product Title:FITC Anti-Mouse CD38 Antibody [NIMR5]
SKU:AGEL2013
Size:25µg, 100µg
Clone No:NIMR5
Synonyms:ADP-ribosyl cyclase 1;ADPRC 1;CD38;NIM-R5 antigen;2'-phospho-cyclic-ADP-ribose transferase;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P56528
Gene ID:12494
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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