APC Anti-Mouse CD38 Antibody [NIMR5] (AGEL2015)

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SKU:
AGEL2015
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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APC Anti-Mouse CD38 Antibody [NIMR5]

The Mouse CD38 Monoclonal Antibody APC Conjugated (NIMR5) is a valuable tool for research involving CD38, a cell surface protein with diverse functions including signal transduction and cell adhesion. This antibody, derived from mouse monoclonal sources, is specifically conjugated with APC for flow cytometry applications, allowing for precise and sensitive detection of CD38 expression in various cell populations.CD38 is known to be involved in immune responses, cell activation, and differentiation, making it a key player in immunology research. Its expression has been linked to various diseases, including autoimmune disorders, infectious diseases, and cancer, highlighting its importance as a biomarker and potential therapeutic target.

By utilizing the Mouse CD38 Monoclonal Antibody APC Conjugated (NIMR5), researchers can gain insights into the role of CD38 in disease pathogenesis and explore novel treatment strategies based on targeting this protein.Overall, this antibody offers a robust and reliable tool for studying CD38 biology, providing valuable information for understanding immune responses, cell signaling pathways, and disease mechanisms. Its versatility in flow cytometry applications makes it a versatile asset for researchers investigating immunology, oncology, and other related fields.

Product Title:APC Anti-Mouse CD38 Antibody [NIMR5]
SKU:AGEL2015
Size:25µg, 100µg
Clone No:NIMR5
Synonyms:ADP-ribosyl cyclase 1;ADPRC 1;CD38;NIM-R5 antigen;2'-phospho-cyclic-ADP-ribose transferase;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P56528
Gene ID:12494
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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