The Mouse CD38 Monoclonal Antibody (APC Conjugated) NIMR5 (AGEL2012) is a specialized tool for researchers studying CD38, a transmembrane glycoprotein involved in various cellular processes, including cell adhesion, signal transduction, and calcium signaling. This antibody, developed specifically for mouse samples, is conjugated with APC for easy detection in flow cytometry and other fluorescence-based applications.CD38 is known for its role in immune regulation, cell activation, and differentiation, making it a key target in immunology and cancer research. The Mouse CD38 Monoclonal Antibody (APC Conjugated) NIMR5 (AGEL2012) provides high specificity and sensitivity for detecting CD38 expression in mouse cells, allowing for detailed analysis and characterization in a variety of experimental contexts.
For researchers investigating the functions and implications of CD38 in immune responses, inflammatory conditions, and disease states, this antibody offers a reliable tool to advance understanding and pave the way for potential therapeutic interventions. Its versatility and effectiveness make it an invaluable asset for studies involving CD38 in mouse models.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P56528
Gene ID:
12494
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.