The Mouse CD335 Monoclonal Antibody (FITC-conjugated 29A1-4) is a specialized research tool offered by Assaygenie. This antibody is tailored for the detection and analysis of CD335, a crucial cell surface protein involved in immune responses. Employing a FITC conjugation for fluorescence detection, the antibody delivers high sensitivity and specificity in various experimental settings.CD335, also known as natural killer cell receptor protein 1 (NKP46), plays a pivotal role in the function of natural killer (NK) cells, a vital component of the immune system responsible for targeting infected or tumor cells. By targeting CD335, researchers can explore the role of NK cells in immune surveillance, anti-tumor immunity, and viral responses.
This antibody enables precise detection and examination of CD335 expression in different cell types, facilitating studies in immunology, infectious diseases, and cancer research.Furthermore, the validation of this antibody ensures reliable and reproducible results in techniques such as flow cytometry and immunofluorescence. With its ability to target CD335 with accuracy and efficiency, the Mouse CD335 Monoclonal Antibody (FITC-conjugated 29A1-4) serves as an indispensable tool for unraveling the intricate mechanisms of immune responses and advancing the understanding of NK cell biology in health and disease.
Product Title:
FITC Anti-Mouse CD335 Antibody [29A1.4]
SKU:
AGEL1936
Size:
25µg, 100µg
Clone No:
29A1.4
Synonyms:
Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q8C567
Gene ID:
17086
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.