APC Anti-Mouse CD335 Antibody [29A1.4] (AGEL1935)

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SKU:
AGEL1935
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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APC Anti-Mouse CD335 Antibody [29A1.4]

The Mouse CD335 Monoclonal Antibody (APC Conjugated) 29A1-4 (AGEL1935) is a powerful tool for researchers studying natural killer (NK) cell biology and immunology. This monoclonal antibody, conjugated to allophycocyanin (APC), specifically targets the CD335 protein, also known as NKp46, which is a key marker for NK cells.NK cells are a type of lymphocyte that plays a critical role in the body's immune response against tumors and virally infected cells. The CD335 protein is a crucial activating receptor expressed on the surface of NK cells, helping them recognize and eliminate target cells. By using the 29A1-4 APC-conjugated antibody, researchers can accurately detect and analyze the expression of CD335 in various cell types, paving the way for deeper insights into NK cell function and biology.

This antibody is ideal for flow cytometry applications, allowing for high-throughput screening and sorting of NK cells based on CD335 expression levels. Its specificity and sensitivity ensure reliable and reproducible results in experimental settings focused on understanding NK cell activation, function, and dysregulation in disease states such as cancer, infectious diseases, and autoimmune disorders.Overall, the Mouse CD335 Monoclonal Antibody (APC Conjugated) 29A1-4 (AGEL1935) is a valuable tool for researchers seeking to advance their understanding of NK cell biology and explore potential therapeutic targets for immune-related diseases.

Product Title:APC Anti-Mouse CD335 Antibody [29A1.4]
SKU:AGEL1935
Size:50 Tests, 100 Tests, 200 Tests
Clone No:29A1.4
Synonyms:Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q8C567
Gene ID:17086
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

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