The Mouse CD3 Monoclonal Antibody (PERCP Conjugated, 17A2-AGEL0658) offered by AssayGenie is a powerful tool for researchers studying immune responses in mice. This antibody specifically targets the CD3 protein, a crucial component of the T-cell receptor complex involved in T-cell activation and function.Designed for flow cytometry applications, this antibody is conjugated to PERCP, enabling high-quality detection and analysis of CD3-expressing cells in mouse samples.
With its strong reactivity and specificity, this monoclonal antibody is an essential tool for investigating T-cell biology, immune responses, and autoimmune diseases in mouse models.By utilizing the Mouse CD3 Monoclonal Antibody from AssayGenie, researchers can gain valuable insights into the functioning of the immune system in mice, advancing our understanding of immune-mediated diseases and paving the way for the development of novel therapies.
Product Title:
PerCP Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL0658
Size:
25µg, 100µg
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PerCP Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.