PE/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2] (AGEL0661)

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SKU:
AGEL0661
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody PE-Cyanine5.5 Conjugated (clone 17A2) is a powerful tool for flow cytometry and immunofluorescence applications in research settings. This antibody specifically targets CD3, a crucial protein found on the surface of T cells, playing a central role in immune response activation. Developed for use in mouse samples, the antibody offers high specificity and sensitivity, allowing for accurate and reliable detection of CD3 in various cell types. The PE-Cyanine5.5 conjugation enhances the detection signal, facilitating detailed analysis of T cell populations.

Ideal for studies in immunology, cancer research, and autoimmune disorders, this antibody provides valuable insights into T cell function and activation. By targeting CD3, researchers can investigate T cell activation, proliferation, and differentiation, advancing our understanding of immune responses in health and disease.Overall, the Mouse CD3 Monoclonal Antibody PE-Cyanine5.5 Conjugated (clone 17A2) is a valuable tool for researchers seeking to unravel the complexities of T cell biology and explore therapeutic targets in immune-related conditions.

Product Title:PE/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0661
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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