Biotin Anti-Mouse CD3 Antibody [17A2] (AGEL0097)

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SKU:
AGEL0097
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
17A2
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (Biotin Conjugated, 17A2) AGEL0097 is a key tool for researchers investigating T-cell biology and immune responses in mice. This antibody, targeting the CD3 antigen, is specifically designed for use in flow cytometry and other immunological assays to detect and characterize T cells in experimental settings.CD3 is an essential component of the T-cell receptor complex and is crucial for T-cell activation and function. The 17A2 monoclonal antibody recognizes the CD3 antigen with high specificity and sensitivity, allowing for precise analysis of T-cell populations in murine samples. By using this antibody, researchers can gain insights into T-cell development, activation, and effector functions in various experimental models.

With its biotin conjugation, this monoclonal antibody offers versatility in experimental setups, allowing for easy integration into a range of detection systems. Its reliability and performance make it an invaluable resource for studies focusing on immune responses, autoimmunity, infectious diseases, and immunotherapy in mouse models.For researchers delving into the intricate world of mouse T-cell biology, the Mouse CD3 Monoclonal Antibody (Biotin Conjugated, 17A2) AGEL0097 is a valuable reagent that promises accurate and reproducible results, advancing our understanding of immune system dynamics and T-cell-mediated immune responses in preclinical research.

Product Title:Biotin Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0097
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Biotin Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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