The Mouse CD3 Monoclonal Antibody (APC-conjugated, 17A2, AGEL0100) from AssayGenie is a powerful tool for researchers studying immune responses and immune cell activation in mouse models. This high-quality antibody is specifically designed for the detection of CD3, a key cell surface marker found on T cells.The 17A2 monoclonal antibody is carefully validated for use in flow cytometry applications, providing reliable and reproducible results. By targeting CD3, this antibody allows for precise identification and analysis of T cells, enabling researchers to study immune cell populations and responses in depth.Utilizing the APC conjugation, this antibody offers strong signal intensity, ensuring accurate and sensitive detection in flow cytometry experiments.
With its specificity for CD3, researchers can confidently investigate T cell activation, differentiation, and function in various experimental settings.Overall, the Mouse CD3 Monoclonal Antibody (APC-conjugated, 17A2, AGEL0100) is a valuable research tool for immunologists, cancer biologists, and scientists studying autoimmune diseases. Its reliability, specificity, and performance make it a crucial component for understanding immune responses and T cell biology in mouse models.
Product Title:
APC Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL0100
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.