The Mouse CD3 Epsilon Monoclonal Antibody (PerCP Cyanine5.5 Conjugated) is a cutting-edge research tool designed for immunology studies involving CD3 epsilon, a critical component of the T-cell receptor complex. This high-quality antibody, designated as 145-2C11 clone and catalog number AGEL1328, is specifically engineered for precise detection and analysis of CD3 epsilon in mouse samples.CD3 epsilon is essential for T-cell development, activation, and function, making it a key target in immunological research. The monoclonal antibody, conjugated with PerCP Cyanine5.
5, offers enhanced sensitivity and specificity in flow cytometry and immunofluorescence applications. Its reactivity with mouse samples ensures reliable and consistent results, allowing researchers to explore the role of CD3 epsilon in immune responses, autoimmunity, infectious diseases, and cancer.With its established performance and versatility, the Mouse CD3 Epsilon Monoclonal Antibody (PerCP Cyanine5.5 Conjugated) 145-2C11 is a valuable tool for elucidating the complexities of T-cell biology and advancing scientific discoveries in immunology and related fields.
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P22646
Gene ID:
12501
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.