The Mouse CD3 Epsilon Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated) (145-2C11) is a cutting-edge antibody specifically designed for researchers in the field of immunology. This monoclonal antibody is highly specialized for targeting CD3 epsilon, a crucial component of the T-cell receptor complex. By conjugating PerCP-Cyanine5.5 to the antibody, it allows for precise and sensitive detection of CD3 epsilon in a variety of cell types.CD3 epsilon is a key marker of T-cell activation and function, making this antibody an invaluable tool for studies involving T-cell biology, immune responses, and immunotherapy research. With its high specificity and sensitivity, researchers can confidently use this antibody for flow cytometry and other applications to investigate T-cell activation, differentiation, and signaling pathways.
By utilizing the Mouse CD3 Epsilon Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated) (145-2C11), researchers can gain valuable insights into T-cell function and immune responses, paving the way for discoveries in immunotherapy, autoimmune diseases, infectious diseases, and cancer research. This antibody is a powerful asset for scientists seeking to unravel the complexities of the immune system and develop innovative treatments for a range of health conditions.
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P22646
Gene ID:
12501
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.