The Mouse CD3-Epsilon Monoclonal Antibody (PE/Cyanine7 Conjugated) 145-2C11 (AGEL1326) is a powerful tool for immunological research, specifically targeting the CD3-Epsilon protein found on T cells. This antibody, conjugated with PE/Cyanine7 for easy visualization, is highly specific and sensitive, ensuring accurate detection and analysis in flow cytometry and other applications.CD3-Epsilon is a crucial component of the T cell receptor complex, playing a central role in T cell activation and signaling. By targeting this protein, researchers can study T cell function, activation, and differentiation in various biological systems. The Mouse CD3-Epsilon Monoclonal Antibody facilitates the identification and quantification of T cells within complex cell populations, making it indispensable for studies on immune responses, autoimmunity, and infectious diseases.
With its high specificity and optimized performance, this antibody provides reliable results and enables precise investigations into T cell biology. Whether exploring basic immunology, vaccine development, or therapeutic strategies, the Mouse CD3-Epsilon Monoclonal Antibody (PE/Cyanine7 Conjugated) 145-2C11 (AGEL1326) is an essential reagent for scientists seeking to deepen their understanding of T cell-mediated immunity.
PE/Cyanine7 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PE/Cyanine 7
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P22646
Gene ID:
12501
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.