PE/Cyanine5.5 Anti-Mouse CD3ε Antibody [145-2C11] (AGEL1319)

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SKU:
AGEL1319
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3 Epsilon Monoclonal Antibody (PE/Cyanine5.5 Conjugated, 145-2C11) from AssayGenie, identified by the product code AGEL1319, is a valuable tool for researchers focusing on immune system studies, particularly those involving T cell biology.This antibody specifically targets CD3 epsilon, a cell surface protein that is a key component of the T cell receptor complex. By binding to CD3 epsilon, the antibody enables the detection and analysis of T cells in various experimental settings. The PE/Cyanine5.5 conjugation of this antibody allows for easy visualization and quantification of the target cells, making it suitable for flow cytometry applications.

The CD3 epsilon protein is essential for T cell activation and function, playing a crucial role in the adaptive immune response. Understanding the dynamics of CD3 epsilon expression and signaling is fundamental for unraveling the mechanisms underlying immune responses and immune-related disorders such as autoimmune diseases and infections.Researchers can rely on the Mouse CD3 Epsilon Monoclonal Antibody from AssayGenie for accurate and reliable results in their T cell research, paving the way for new insights into immune system function and potential therapeutic strategies.

Product Title:PE/Cyanine5.5 Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL1319
Size:50 Tests, 100 Tests, 200 Tests
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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