The Mouse CD3-epsilon Monoclonal Antibody (APC-conjugated, clone 145-2C11, AGEL1316) offered by Assay Genie is a powerful tool for immunology research. Targeting the CD3-epsilon marker, this antibody is designed for applications in flow cytometry, immunofluorescence, and other techniques requiring fluorescent detection. CD3-epsilon is a crucial component of the T-cell receptor complex and is instrumental in T-cell activation. By specifically binding to CD3-epsilon, this monoclonal antibody enables precise identification and analysis of T-cell populations in various samples.
Its APC conjugation allows for easy and efficient detection in multicolor flow cytometry experiments.Ideal for studies involving T-cell biology, immunotherapy, and immune cell characterization, the Mouse CD3-epsilon Monoclonal Antibody from Assay Genie provides accurate and reliable results for researchers looking to investigate T-cell responses and functions in both health and disease contexts.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P22646
Gene ID:
12501
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.