GenieFluor 647 Anti-Mouse CD3ε Antibody [145-2C11] (AGEL1330)

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SKU:
AGEL1330
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3 Epsilon Monoclonal Antibody (AF647 Conjugated, 145-2C11) is a versatile tool for researchers investigating T cell biology and immunology. This antibody, provided by Assay Genie, specifically targets the CD3 epsilon chain, a crucial component of the T cell receptor complex.With its AF647 conjugation, this antibody enables precise detection and visualization of CD3 epsilon in various experimental settings, such as flow cytometry and immunofluorescence. Its monoclonal nature ensures high specificity and low background, resulting in reliable and reproducible results.

The CD3 epsilon chain is essential for T cell development, activation, and function, making this antibody invaluable for studying T cell responses in immune-mediated diseases, infectious diseases, and cancer. Its compatibility with various research techniques makes it a versatile tool for investigating the intricate mechanisms of T cell biology.Researchers exploring T cell function, immunotherapy, and autoimmunity will find the Mouse CD3 Epsilon Monoclonal Antibody (AF647 Conjugated, 145-2C11) from Assay Genie to be a valuable addition to their experimental toolkit.

Product Title:GenieFluor 647 Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL1330
Size:25µg, 100µg
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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