GenieFluor 488 Anti-Mouse CD3ε Antibody [145-2C11] (AGEL1329)

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SKU:
AGEL1329
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
145-2C11
Conjugation:
AF 488
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3 epsilon Monoclonal Antibody (AF488 Conjugated) 145-2C11 (AGEL1329) from AssayGenie is a cutting-edge tool designed for research involving the CD3 epsilon protein, a crucial component of the T-cell receptor complex. This monoclonal antibody, conjugated with AF488 for fluorescent detection, is engineered to specifically target and bind to CD3 epsilon in mouse samples.With its high reactivity and specificity, this antibody is validated for various applications, including flow cytometry, immunofluorescence, and immunohistochemistry, allowing for the precise detection and visualization of CD3 epsilon in different cell types and tissues.

Researchers in immunology, oncology, and related fields can leverage this antibody to investigate T-cell activation, differentiation, and function in both normal and pathological conditions.The CD3 epsilon Monoclonal Antibody AF488 Conjugated 145-2C11 represents a valuable tool for studies aiming to unravel the complex mechanisms underlying immune responses, T-cell biology, and immune-related disorders. Its reliable performance and versatility make it an essential component of experimental strategies seeking to advance our understanding of immune system dynamics and potential therapeutic interventions.

Product Title:GenieFluor 488 Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL1329
Size:25µg, 100µg
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 488 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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