The Mouse CD3 Epsilon Monoclonal Antibody (145-2C11) offered by AssayGenie (AGEL0374) is a high-quality antibody designed for research applications involving CD3 epsilon, a critical component of the T-cell receptor complex. This monoclonal antibody, specifically targeting CD3 epsilon, is produced using advanced techniques to ensure high specificity and sensitivity in various experimental settings.CD3 epsilon is essential for T-cell development, activation, and function, making it a key marker for immunological studies. The 145-2C11 antibody enables reliable detection and analysis of CD3 epsilon expression in mouse samples, allowing researchers to investigate T-cell activities, immune responses, and disease mechanisms with precision.
With its proven performance in techniques such as flow cytometry, immunohistochemistry, and immunoprecipitation, this monoclonal antibody is a valuable tool for immunologists, cancer researchers, and scientists studying autoimmune diseases. By targeting CD3 epsilon, researchers can gain valuable insights into T-cell biology, immune system function, and potential therapeutic strategies for a wide range of conditions.Choose the Mouse CD3 Epsilon Monoclonal Antibody (145-2C11) from AssayGenie for reliable and accurate detection of CD3 epsilon in your research projects, facilitating in-depth exploration of T-cell biology and immune responses.
Purified Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.