GenieFluor 488 Anti-Mouse CD28 Antibody [37.51] (AGEL0139)

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SKU:
AGEL0139
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
37.51
Conjugation:
AF 488
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD28 Antibody [37.51]

The Mouse CD28 Monoclonal Antibody (Alexa Fluor 488 Conjugated) (37-51) is a cutting-edge tool designed for researchers studying the CD28 protein, a vital co-stimulatory molecule involved in T cell activation and immune response regulation. This antibody, derived from mouse monoclonal sources, exhibits high specificity and sensitivity in binding to the CD28 protein in mouse samples. Its conjugation with Alexa Fluor 488 allows for fluorescent visualization and localization of CD28 within cells, enabling detailed analysis and imaging in various experimental setups.CD28 is a key player in T cell activation, providing essential signals for robust immune responses and effective coordination of immune functions. Its presence and activity influence the outcome of immune reactions, making it a significant target for investigation in immunology research, vaccine development, and autoimmune disease studies.

By targeting CD28 with this specific antibody, researchers can gain insights into the molecular mechanisms underlying T cell activation, paving the way for new therapeutic strategies and potential interventions in immune-related disorders.Overall, the Mouse CD28 Monoclonal Antibody (Alexa Fluor 488 Conjugated) (37-51) serves as a valuable asset for scientists exploring the intricacies of immune system function, particularly in the realm of T cell biology and immune regulation. Its precision, reliability, and versatility make it an indispensable resource for advancing our understanding of CD28-mediated immune responses and its implications in health and disease.

Product Title:GenieFluor 488 Anti-Mouse CD28 Antibody [37.51]
SKU:AGEL0139
Size:50 Tests, 100 Tests, 200 Tests
Clone No:37.51
Synonyms:T-cell-specific surface glycoprotein CD28;Cd28;CD28;
Host Species:Syrian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Isotype Control:Genie Fluor 488 Syrian Hamster IgG Isotype Control[SHG-1]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31041
Gene ID:12487
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.

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