GenieFluor 647 Anti-Mouse CD28 Antibody [37.51] (AGEL0774)

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SKU:
AGEL0774
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG2a,k
Clone:
37.51
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD28 Antibody [37.51]

The Mouse CD28 Monoclonal Antibody (AF647-conjugated, 37-51) from Assay Genie (AGEL0774) is a cutting-edge tool designed for research involving CD28, a crucial co-stimulatory molecule involved in T cell activation and immune response modulation. This monoclonal antibody, conjugated with AF647 for enhanced detection capabilities, is specifically engineered for use in flow cytometry and immunofluorescence applications.CD28 is a key player in the regulation of T cell activation and immune responses, making it a pivotal target for investigation in immunology and related fields. By targeting the CD28 protein, this antibody allows for precise detection and analysis of CD28 expression in mouse samples, enabling researchers to delve deeper into the mechanisms underlying immune regulation, tolerance, and inflammation.

With its high specificity and sensitivity, the Mouse CD28 Monoclonal Antibody (AF647-conjugated, 37-51) offers researchers a powerful tool for studying the intricate pathways involved in immune activation and T cell function. By unraveling the role of CD28 in various biological processes, this antibody aids in advancing our understanding of immune system dynamics and holds promise for informing therapeutic strategies targeting immune-mediated disorders, cancer immunotherapy, and vaccine development.

Product Title:GenieFluor 647 Anti-Mouse CD28 Antibody [37.51]
SKU:AGEL0774
Size:25µg, 100µg
Clone No:37.51
Synonyms:T-cell-specific surface glycoprotein CD28;Cd28;CD28;
Host Species:Syrian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Isotype Control:Genie Fluor 647 Syrian Hamster IgG Isotype Control[SHG-1]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P31041
Gene ID:12487
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.

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