The Mouse CD25 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, PC61.5.3, AGEL1302) offered by Assay Genie is a powerful tool for researchers studying immune system dynamics and cell signaling pathways. This antibody specifically targets CD25, a key cell surface marker associated with regulatory T cells (Tregs) and activated T lymphocytes. By binding to CD25, this antibody allows for precise detection and analysis of CD25-expressing cells in a variety of experimental settings.CD25, also known as the interleukin-2 receptor alpha chain, plays a crucial role in immune regulation and tolerance induction. It is essential for the development and function of Tregs, which are pivotal in maintaining immune balance and preventing autoimmunity. CD25 is also upregulated on activated T cells, contributing to their proliferation and effector functions. Therefore, understanding the expression and function of CD25 is vital for unraveling the complexities of immune responses and immunological disorders.
The Mouse CD25 Monoclonal Antibody provided by Assay Genie is conjugated with PerCP-Cyanine5.5, allowing for multi-parameter flow cytometry analysis and cell sorting. This high-quality antibody has been rigorously validated for its specificity and sensitivity, ensuring accurate and reliable results in various research applications. Whether investigating T cell activation, regulatory mechanisms, or immune tolerance, this antibody is an indispensable tool for immuno-oncology, autoimmune disease, and immunotherapy studies.Researchers looking to delve deeper into the intricate interactions of immune cells and their regulatory networks can rely on the Mouse CD25 Monoclonal Antibody from Assay Genie to facilitate their investigations with precision and confidence. Unlock the potential of CD25-related research and advance our understanding of immune system function with this exceptional antibody reagent.
PerCP/Cyanine5.5 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01590
Gene ID:
16184
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD25 is a 55 kD glycoprotein, also known as the low affinity IL-2Rα, Ly-43, p55, or Tac. It is expressed on activated T and B cells, thymocyte subset, pre-B cells, and T regulatory cells. In association with CD122 (IL-2Rβ) and CD132(common γ chain), CD25 forms the high affinity signaling IL-2 receptor.