The Mouse CD25 Monoclonal Antibody PE Conjugated (PC 61.5.3) (AGEL1306) is a powerful tool for researchers studying immune cell markers and immune responses in mice. This high-quality monoclonal antibody specifically targets CD25, a cell surface protein also known as the interleukin-2 receptor alpha chain. With its PE conjugation, this antibody is optimized for flow cytometry applications, allowing for precise and sensitive detection of CD25 expression on a variety of immune cell populations. By targeting CD25, researchers can identify and analyze regulatory T cells, activated T cells, and other immune cell subsets involved in immune regulation and tolerance.
This monoclonal antibody is ideal for studies in immunology, autoimmunity, transplantation, and cancer research, where understanding the role of CD25-expressing cells is crucial. By utilizing the Mouse CD25 Monoclonal Antibody PE Conjugated (PC 61.5.3), researchers can delve deeper into the mechanisms of immune regulation and develop new insights into immune-mediated diseases and therapeutic strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P01590
Gene ID:
16184
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD25 is a 55 kD glycoprotein, also known as the low affinity IL-2Rα, Ly-43, p55, or Tac. It is expressed on activated T and B cells, thymocyte subset, pre-B cells, and T regulatory cells. In association with CD122 (IL-2Rβ) and CD132(common γ chain), CD25 forms the high affinity signaling IL-2 receptor.