The Mouse CD24 Monoclonal Antibody (PE Conjugated, M1/69) is a powerful tool for researchers studying CD24, a cell surface protein known for its role in cell adhesion, signal transduction, and immune regulation. This monoclonal antibody, conjugated with PE for enhanced detection, is specifically designed for flow cytometry applications, enabling precise identification and characterization of CD24-expressing cells in biological samples.CD24, also referred to as a cell adhesion molecule or a heat-stable antigen, is involved in various physiological processes, including cell proliferation, differentiation, and migration. Its expression pattern has been linked to different disease states, such as cancer, inflammation, and immune disorders, making it a target of interest in biomedical research.
By utilizing the Mouse CD24 Monoclonal Antibody (PE Conjugated, M1/69), researchers can gain insights into the role of CD24 in disease pathogenesis, immune responses, and tissue homeostasis.This antibody, generated in mice, offers high specificity and sensitivity in detecting CD24 expression, facilitating accurate analysis of cell populations in diverse experimental settings. With its reliable performance and compatibility with flow cytometry techniques, the Mouse CD24 Monoclonal Antibody (PE Conjugated, M1/69) is a valuable tool for investigating the functions and regulation of CD24 in various cellular contexts, providing essential data for advancing research in immunology, oncology, and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P24807
Gene ID:
12484
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD24 is a 35-45 kD protein also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, and dendritic cells. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.