The Mouse CD24 Monoclonal Antibody (AF488 Conjugated) (M1/69) (AGEL1898) is a cutting-edge tool designed for research applications involving CD24, a cell surface marker known for its roles in cell adhesion, differentiation, and cancer progression. This monoclonal antibody, conjugated with AF488 for fluorescence detection, offers high specificity and sensitivity in detecting CD24 in mouse samples, making it a valuable asset in immunology and cancer research.CD24, a glycosylphosphatidylinositol-anchored protein, is involved in various cellular processes, including regulating cell proliferation, migration, and immune response.
Its overexpression has been linked to tumor aggressiveness and metastasis in several cancer types, making it a promising target for therapeutic interventions. The Mouse CD24 Monoclonal Antibody (AF488 Conjugated) (M1/69) (AGEL1898) provides researchers with a reliable tool for investigating the expression and function of CD24 in different experimental settings, contributing to the understanding of its implications in disease progression and potential treatment strategies.
Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24807
Gene ID:
12484
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD24 is a 35-45 kD protein also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, and dendritic cells. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.