The Mouse CD23 Monoclonal Antibody (FITC Conjugated) B3B4 (AGEL1888) offered by Assay Genie is a specialized tool for research into CD23, a cell surface protein known for its involvement in immune responses, particularly in the context of B cell function and allergen recognition. This monoclonal antibody, derived from hybridoma cell culture, exhibits high specificity and sensitivity when detecting CD23, making it an essential reagent for studies involving this protein.CD23, also referred to as Fc epsilon RII, plays a crucial role in regulating immunoglobulin E (IgE) production and mediating allergic responses. Its presence on B cells and other immune cells underscores its importance in modulating immune reactions and inflammatory processes. Researchers studying allergy mechanisms, B cell biology, and immune system dysregulation can benefit greatly from the precision and reliability of the FITC-conjugated B3B4 monoclonal antibody in accurately detecting and visualizing CD23 expression.
The fluorescence conjugation of this antibody allows for easy visualization and quantification of CD23 expression in flow cytometry, immunofluorescence, and other fluorescence-based techniques. Its compatibility with mouse samples further enhances its utility in preclinical studies and mouse model research. By targeting CD23, researchers can explore novel therapeutic targets for conditions related to allergic responses, B cell disorders, and immune system malfunctions. Gain valuable insights into CD23 biology and its implications in immunology and allergy research with the Mouse CD23 Monoclonal Antibody (FITC Conjugated) B3B4 (AGEL1888) from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P20693
Gene ID:
14128
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD23 is a 45 kD protein also known as low affinity IgE Fc receptor, FcεRII, BLAST-2, Ly-42, or B6. It is a member of the Ig family, expressed on conventional B (but not B-1) cells and follicular dendritic cells. CD23 responds to high levels of IgE by downregulating IgE secretion.