The Mouse CD23 Monoclonal Antibody FITC Conjugated (B3B4) is a specialized antibody designed for research applications involving the CD23 molecule in mice. CD23, also known as Fc epsilon RII, is a cell surface protein involved in B cell activation and immune response regulation. This monoclonal antibody, conjugated with FITC for fluorescent detection, specifically targets CD23 on mouse cells, allowing for precise identification and analysis in various experimental settings.The B3B4 antibody is highly specific and sensitive, making it a versatile tool for immunological studies, particularly in research related to B cell function, allergic responses, and immunotherapy. Its conjugation with FITC enhances its utility in flow cytometry, fluorescence microscopy, and other fluorescence-based assays, enabling researchers to visualize and quantify CD23 expression with high resolution and accuracy.
By targeting CD23, researchers can delve into the mechanisms underlying B cell activation, antibody production, and immune regulation in mice. Understanding the role of CD23 in immune processes is pivotal for unraveling complex pathways associated with autoimmune diseases, allergic conditions, and immune-mediated disorders. The Mouse CD23 Monoclonal Antibody FITC Conjugated (B3B4) serves as an essential tool for investigating the function and significance of CD23 in mouse models, facilitating advancements in immunology and therapeutic development.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20693
Gene ID:
14128
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD23 is a 45 kD protein also known as low affinity IgE Fc receptor, FcεRII, BLAST-2, Ly-42, or B6. It is a member of the Ig family, expressed on conventional B (but not B-1) cells and follicular dendritic cells. CD23 responds to high levels of IgE by downregulating IgE secretion.