The Mouse CD1d Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated, 19G11, AGEL0822) available at AssayGenie is a cutting-edge tool for researchers working with mouse models to investigate CD1d, a crucial cell surface glycoprotein involved in antigen presentation and immune regulation. This monoclonal antibody has been specifically engineered for fluorescence-based assays, enabling precise and reliable detection of CD1d in various experimental setups.CD1d is a key player in the immune system, responsible for presenting lipid antigens to specialized T cells known as iNKT cells. By interacting with CD1d, these cells can quickly orchestrate immune responses against infections, tumors, and autoimmune disorders.
The 19G11 monoclonal antibody facilitates the visualization and quantification of CD1d expression, allowing researchers to delve deeper into the mechanisms underlying immune responses and potential therapeutic targets.With its high specificity and sensitivity, the Mouse CD1d Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated, 19G11, AGEL0822) is a valuable asset for studies focusing on immunology, infectious diseases, and cancer immunotherapy. By leveraging the power of this antibody, researchers can uncover new insights into the role of CD1d in immune surveillance, tolerance, and disease pathogenesis, paving the way for innovative strategies in personalized medicine and immunotherapy research.
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P11609
Gene ID:
12479
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.