The Mouse CD19 Monoclonal Antibody PE/Cyanine7 Conjugated 1D3 (AGEL0466) is a specialized antibody designed for research applications involving CD19, a cell surface protein commonly used as a B cell marker. This antibody, conjugated to PE/Cyanine7 for fluorescent detection, offers high specificity and sensitivity in detecting CD19 in mouse samples. It is ideal for flow cytometry and immunofluorescence experiments, allowing for precise identification and analysis of B cell populations in different tissues and experimental conditions.CD19, a key component of the B cell receptor complex, is essential for B cell development, activation, and differentiation.
Research on CD19 is vital in understanding B cell biology, immune responses, and diseases related to B cell dysregulation such as leukemia and autoimmune disorders. The Mouse CD19 Monoclonal Antibody PE/Cyanine7 Conjugated 1D3 (AGEL0466) provides researchers with a powerful tool to investigate the role of CD19 in various physiological and pathological processes, contributing to advancements in immunology and related fields.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.