The Mouse CD19 Monoclonal Antibody (PE Conjugated, 1D3) is a powerful tool for researchers studying immune cells and antibody therapy. It specifically targets the CD19 protein, a key marker found on B cells and used for identifying and tracking these cells in various experimental settings.This monoclonal antibody, conjugated to Phycoerythrin (PE), offers high sensitivity and specificity in flow cytometry analyses, making it ideal for immunophenotyping studies and investigating B cell development, activation, and response to treatment. The PE conjugation allows for easy visualization and quantification of CD19-expressing cells, providing valuable insights into immune responses and disease pathology.
Additionally, the Mouse CD19 Monoclonal Antibody (PE Conjugated, 1D3) is rigorously validated for its performance in flow cytometry applications, ensuring reliable and reproducible results for your research needs. Whether studying normal immune responses, cancer immunotherapy, or autoimmune diseases, this antibody is a valuable asset for understanding the role of CD19 in immune function and disease progression.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.