The Mouse CD19 Monoclonal Antibody, GenieFluor 488 Conjugated (1D3) is expertly designed for research involving CD19, a vital cell surface molecule essential for B-cell development, activation, and differentiation. This monoclonal antibody, developed in mice, is conjugated with GenieFluor 488, providing bright and stable green fluorescence for precise detection in flow cytometry applications.CD19 serves as a crucial marker for B-cell lineage identification and is instrumental in B-cell signal transduction. The GenieFluor 488 conjugation enhances the utility of this antibody in highly sensitive fluorescence-based assays, making it ideal for studies in immunology, oncology, and autoimmune research.
The Mouse CD19 Monoclonal Antibody, GenieFluor 488 Conjugated (1D3), facilitates accurate detection and detailed analysis of B-cells, supporting research into B-cell malignancies such as lymphomas and leukemias, as well as autoimmune disorders like rheumatoid arthritis and lupus.Understanding the role and activity of CD19 is essential for the development of targeted therapies aimed at modulating B-cell function. This antibody is an invaluable tool for researchers striving to elucidate B-cell mechanisms and advance treatment strategies for B-cell-related diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.