The Mouse CD19 Monoclonal Antibody (AF647 Conjugated 1D3, AGEL0478) offered by AssayGenie is a powerful tool for research involving the CD19 protein, a key cell surface marker found on B cells. This monoclonal antibody, conjugated with AF647 for fluorescent detection, is specifically designed for flow cytometry applications, enabling precise identification and analysis of CD19-expressing cells.CD19 is a crucial protein involved in B cell development, activation, and function, making it a valuable target for studies in immunology, hematopoiesis, and cancer research. The AF647-conjugated 1D3 monoclonal antibody provides high specificity and sensitivity in detecting CD19, allowing researchers to investigate B cell populations in various tissues and disease states.
By targeting CD19, researchers can gain valuable insights into B cell biology, immune responses, and B cell-related diseases such as leukemia, lymphoma, and autoimmune disorders. The Mouse CD19 Monoclonal Antibody (AF647 Conjugated 1D3, AGEL0478) from AssayGenie is a reliable tool for advancing research in these areas and accelerating discoveries in the field of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.