The Mouse CD19 Monoclonal Antibody (AF647 Conjugated, 1D3) is a versatile tool for immunological research, particularly in the study of B cell biology and related diseases. This antibody, conjugated to AF647 for easy detection and visualization, specifically targets the CD19 protein on the surface of B cells.CD19 is a crucial marker for B cell development and activation, making this antibody essential for studying B cell function in various research applications. The AF647 conjugation allows for precise imaging and analysis of CD19-expressing cells, aiding in the identification and characterization of B cell populations in both in vitro and in vivo experiments.
With its high specificity and sensitivity, the Mouse CD19 Monoclonal Antibody (AF647 Conjugated, 1D3) is a valuable tool for researchers exploring B cell biology, immune responses, and the development of novel therapies for B cell-related disorders. Its use can provide valuable insights into the role of CD19 in immune regulation and the pathogenesis of conditions such as leukemia, lymphoma, and autoimmune diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.