The Mouse CD19 Monoclonal Antibody (AF488 Conjugated, 1D3) is a highly specific and efficient tool for researchers studying immune responses and B cell-related processes. This antibody, conjugated with AF488 for fluorescence-based applications, targets the CD19 protein expressed on the surface of B cells. CD19 is a key marker for B cell identification and activation, making this antibody essential for flow cytometry, immunofluorescence, and other detection techniques. With the 1D3 clone's high specificity and binding affinity to CD19, researchers can accurately analyze and quantify B cell populations in various samples, including tissues and cell cultures.
The use of the Mouse CD19 Monoclonal Antibody (AF488 Conjugated, 1D3) is crucial in understanding B cell dynamics, immune responses, and diseases related to B cell dysfunction, such as B cell lymphomas and autoimmune disorders. Its reliable performance and fluorescence conjugation make it a valuable tool for immunologists, cancer researchers, and others interested in exploring B cell biology and related therapeutic targets.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.