PE Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL0430)

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SKU:
AGEL0430
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
CXCR3-173
Conjugation:
PE
Applications:
FC
Frequently bought together:

Description

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PE Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 Monoclonal Antibody (PE-conjugated) is a specialized research tool offered by Assay Genie. This antibody, known as CXCR3-173 (AGEL0430), is designed for the detection and analysis of CD183, a chemokine receptor involved in immune responses and inflammatory processes. This monoclonal antibody is specifically engineered for use with mouse samples and is conjugated with the fluorescent dye PE (phycoerythrin) for easy visualization and analysis in flow cytometry and other fluorescence-based assays.CD183, also known as CXCR3, plays a crucial role in directing immune cell migration to sites of inflammation and infection. Its involvement in inflammatory pathways and immune cell activation makes it a key target for research in immunology, infectious diseases, and inflammatory conditions.

By utilizing this antibody, researchers can accurately detect and study the expression and function of CD183 in various cellular contexts, providing valuable insights into immune responses and potential therapeutic targets.For researchers studying immune cell behavior, chemokine receptors, or inflammatory processes, the Mouse CD183 Monoclonal Antibody (PE-conjugated) offers a reliable and validated tool for precise and efficient analysis, contributing to advancements in understanding immune regulation and inflammatory mechanisms.

Product Title:PE Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL0430
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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