The Mouse CD183 Monoclonal Antibody (APC Conjugated, CXCR3-173) offered by AssayGenie (Product code: AGEL0431) is a cutting-edge tool designed for precise and efficient detection of the CXCR3 marker in mouse samples. This monoclonal antibody has been rigorously validated for use in flow cytometry and immunofluorescence applications, ensuring accurate and reliable results in your research.CXCR3 is a chemokine receptor involved in the modulation of immune responses and plays a crucial role in various physiological and pathological processes, such as inflammation, immune cell migration, and tumor immunity. By targeting CXCR3 with this high-quality APC-conjugated antibody, researchers can effectively analyze and quantify the expression of this key marker in different cell populations.
Whether investigating immune cell trafficking, studying inflammatory responses, or exploring the tumor microenvironment, the Mouse CD183 Monoclonal Antibody (APC Conjugated, CXCR3-173) from AssayGenie provides researchers with a powerful tool to delve deeper into the complexities of immune regulation and disease progression in mouse models. Trust in this antibody to enhance the precision and sensitivity of your experiments, enabling meaningful insights into CXCR3 biology and its implications in various pathological conditions.
Product Title:
APC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:
AGEL0431
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
CXCR3-173
Synonyms:
C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
APC Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
O88410
Gene ID:
12766
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.