PerCP/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1434)

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SKU:
AGEL1434
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
CXCR3-173
Conjugation:
PerCP/Cy5.5
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) (CXCR3-173) is a vital tool for researchers studying the CXCR3 molecule, a chemokine receptor involved in immune responses and inflammatory processes. This antibody, derived from mouse monoclonal sources, exhibits high specificity for mouse samples and is optimized for flow cytometry applications. Its binding capability to CXCR3 allows for precise identification and characterization of CXCR3-expressing cells, facilitating investigations in immunology, inflammation, and immune cell trafficking.CXCR3, a chemokine receptor associated with T cell migration and activation, plays a crucial role in immune surveillance and response to pathogens.

Its involvement in inflammatory conditions, autoimmune disorders, and cancer progression underscores its importance as a therapeutic target. By targeting CXCR3, researchers can explore new avenues for modulating immune cell behavior and potentially developing novel treatments for various immune-related diseases. Understanding the function of CXCR3 is key to unraveling its complex roles in immune regulation and paving the way for innovative therapies targeting this receptor.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1434
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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