PE/Cyanine7 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1424)

(No reviews yet) Write a Review
SKU:
AGEL1424
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine7 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody - PE/Cyanine7 Conjugated (CXCR3-173) is a specialized tool for researchers delving into the intricacies of CXCR3, a chemokine receptor with essential roles in immune responses and inflammation regulation. This monoclonal antibody, generated for mouse samples, is conjugated with PE/Cyanine7 for fluorescent detection in flow cytometry and other analytical techniques. It specifically targets the CXCR3 protein, enabling researchers to identify and study CXCR3 expression in diverse cellular contexts, making it a valuable asset for investigations in immunology and inflammatory diseases.

CXCR3 is a key player in directing immune cell migration and activation in response to various stimuli, including infections, autoimmune disorders, and cancer. Understanding the functions and signaling pathways associated with CXCR3 is pivotal for unraveling the complexities of immune responses and developing targeted therapies for conditions where CXCR3 dysregulation is implicated. By using the CXCR3-173 antibody, researchers can gain insights into the dynamics of CXCR3 expression, localization, and activation, paving the way for advancements in immunotherapy and disease treatment strategies.

Product Title:PE/Cyanine7 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1424
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Cyanine7 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

0 Reviews

View AllClose

Related Products