PE/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1433)

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SKU:
AGEL1433
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody PE/Cyanine5.5 Conjugated (CXCR3-173) from AssayGenie is a powerful tool for researchers studying CXCR3, a chemokine receptor known for its role in inflammation and immune responses. This monoclonal antibody, conjugated with PE/Cyanine5.5 for fluorescent detection, is specifically designed for flow cytometry applications in mouse samples.CXCR3 is a key chemokine receptor involved in the recruitment and activation of immune cells, playing a critical role in various physiological and pathological processes, including host defense, autoimmunity, and cancer progression. By targeting CXCR3, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially develop targeted therapies.

The CXCR3-173 monoclonal antibody offers high specificity and sensitivity for detecting CXCR3 expression in different cell populations, allowing for precise analysis and characterization of immune cell subsets. Its reliability and performance make it an essential tool for immunology research, particularly in investigating immune cell migration, immune responses, and inflammatory pathways.For scientists studying immune cell signaling, inflammation, or seeking to unravel the complexities of immune-related diseases, the Mouse CD183 (CXCR3) Monoclonal Antibody PE/Cyanine5.5 Conjugated (CXCR3-173) is a valuable reagent that can advance their research endeavors and contribute to a better understanding of immune system regulation.

Product Title:PE/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1433
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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