The Mouse CXCR3 Monoclonal Antibody (PE-Cyanine5.5 Conjugated) is a valuable tool for researchers studying CXCR3, a chemokine receptor involved in immune responses and inflammation. This monoclonal antibody, specifically designed for mouse samples, is highly specific and sensitive, making it ideal for flow cytometry and immunofluorescence applications.CXCR3 is a key player in recruiting immune cells to sites of inflammation and infection, making it a promising target for research in areas such as immunology, infectious diseases, and autoimmune disorders.
By utilizing this antibody, researchers can accurately detect and analyze CXCR3 expression in various cell types, providing insights into its function and potential therapeutic applications.Furthermore, understanding the role of CXCR3 in immune regulation and disease pathology is crucial for the development of targeted therapies and treatment strategies. The Mouse CXCR3 Monoclonal Antibody offers researchers a reliable tool to advance their studies and contribute to the growing body of knowledge in immunology and related fields.
C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
PE/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
O88410
Gene ID:
12766
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.