GenieFluor 647 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1427)

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SKU:
AGEL1427
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The CXCR3 Monoclonal Antibody (AGEL1427) is a powerful tool for researchers studying the CXCR3 protein, a key chemokine receptor involved in immune responses and inflammation regulation. This antibody, conjugated with AF647 for enhanced detection, is specifically designed for use in flow cytometry and immunofluorescence applications. It provides high specificity and sensitivity in detecting CXCR3 expression in mouse samples, facilitating detailed analysis of immune cell populations and inflammatory processes.CXCR3 is a chemokine receptor that plays a pivotal role in directing immune cell migration and activation in response to various inflammatory signals. Its involvement in mediating immune cell recruitment to sites of infection or injury makes it a crucial target for understanding immune system function in health and disease.

Research on CXCR3 is particularly relevant in studies related to autoimmune diseases, infectious diseases, and inflammation-related disorders, where modulation of immune cell trafficking and function is of significant interest.By using the CXCR3 Monoclonal Antibody (AGEL1427), researchers can explore the dynamics of CXCR3 expression and analyze its impact on immune cell behavior, offering valuable insights into the mechanisms underlying immune responses and potential therapeutic targets for the treatment of immune-related conditions.

Product Title:GenieFluor 647 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1427
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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