GenieFluor 647 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL0483)

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SKU:
AGEL0483
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
PK136
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD161/NK1.1 Antibody [PK136]

The Mouse CD161 (NK1.1) Monoclonal Antibody (AF647 Conjugated) (PK136) (AGEL0483) is a powerful tool for researchers studying natural killer (NK) cell biology and immune responses in mice. This monoclonal antibody specifically targets the CD161 (NK1.1) protein, which is a well-known marker for certain subsets of NK cells and a range of other immune cells. With its AF647 conjugation, this antibody provides excellent fluorescence properties, allowing for sensitive detection and analysis in flow cytometry and immunofluorescence applications.

The PK136 clone ensures high specificity and reliability in identifying CD161 (NK1.1)-positive cells in various experimental setups.By using this antibody, researchers can deepen their understanding of NK cell function, immune surveillance, and the role of CD161 (NK1.1) in immune responses. This antibody is a valuable tool for investigating immune cell interactions, inflammatory processes, and the development of potential immunotherapies.

Product Title:GenieFluor 647 Anti-Mouse CD161/NK1.1 Antibody [PK136]
SKU:AGEL0483
Size:50 Tests, 100 Tests, 200 Tests
Clone No:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 647 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27814 P27812 Q99JB4
Gene ID:17059
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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