The Mouse CD16/32 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, 2.4G2) from Assay Genie (AGEL0584) is a powerful tool for researchers delving into immune responses and cellular interactions in mouse models. This antibody, designed specifically for use in flow cytometry applications, targets the CD16/32 protein, also known as Fc gamma III/II receptor, which plays a key role in mediating immune responses.Mouse CD16/32 Monoclonal Antibody is ideal for investigating the activation and regulation of immune cells, particularly macrophages and NK cells, through Fc receptor signaling pathways. By binding to CD16/32, this antibody enables precise detection and analysis of these immune cell subsets, aiding in the study of immune function, inflammatory processes, and antibody-dependent cytotoxicity in experimental settings.
With its PerCP-Cyanine5.5 conjugation, this antibody offers the advantage of multicolor flow cytometry capabilities, allowing for simultaneous profiling of different cell surface markers and characterization of complex immune cell populations. Researchers focused on immunology, inflammation, infectious diseases, and antibody therapies will find the Mouse CD16/32 Monoclonal Antibody a valuable asset in their quest for deeper insights into immune system dynamics in mouse models.Unlock the potential of your research with the Mouse CD16/32 Monoclonal Antibody from Assay Genie, designed to enhance your understanding of immune cell function and immune-mediated processes in mouse studies.
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.