PE/Cyanine5.5 Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0593)

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SKU:
AGEL0593
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
2.4G2
Conjugation:
PE/Cy5.5
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD16/32 Antibody [2.4G2]

The Mouse CD16/32 Monoclonal Antibody PE-Cyanine5.5 Conjugated (2.4G2) is a powerful tool for immunological studies involving mouse samples. This antibody, derived from hybridoma cell culture, specifically targets CD16/32, also known as Fc receptors on mouse immune cells. The conjugation with PE-Cyanine5.5 allows for fluorescent detection and analysis in flow cytometry and other fluorescence-based assays.CD16/32, crucial for antibody-dependent cellular cytotoxicity and phagocytosis, plays a key role in the activation and regulation of immune responses in mice. By utilizing this monoclonal antibody, researchers can accurately identify and characterize CD16/32-expressing cells in various tissues and experimental models.

This enables detailed investigations into immune cell function, immune cell subsets, and immune responses in immunology and infectious disease research.Understanding the expression and function of CD16/32 in murine immune systems is essential for advancing our knowledge of immunity, inflammation, and antibody-based therapies. The Mouse CD16/32 Monoclonal Antibody PE-Cyanine5.5 Conjugated (2.4G2) offers a reliable tool for researchers seeking to delve deeper into the intricate mechanisms of mouse immune regulation and responses.

Product Title:PE/Cyanine5.5 Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:AGEL0593
Size:25µg, 100µg
Clone No:2.4G2
Synonyms:CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P08508 P08101
Gene ID:14130,14131
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

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