The FITC-conjugated Mouse CD16/32 Monoclonal Antibody (2.4G2) is a specialized tool designed for researchers working with mouse samples in immunology studies. This monoclonal antibody, known as AGEL0587, targets the CD16/32 proteins on mouse cells, crucial for understanding immune responses and cell signaling pathways.The CD16/32 proteins, also referred to as Fc receptors, play a pivotal role in mediating immune responses by binding to antibodies and promoting various immune functions such as phagocytosis and antibody-dependent cell-mediated cytotoxicity. By using this FITC-conjugated antibody in techniques like flow cytometry, researchers can effectively detect and analyze CD16/32 expression on different cell types, aiding in the investigation of cellular interactions and immune system regulation.
With its high specificity and sensitivity, the Mouse CD16/32 Monoclonal Antibody (2.4G2) is a valuable tool for research into immunology, inflammation, and autoimmune disorders in mouse models. Its application can provide insights into the role of CD16/32 in immune cell activation and function, contributing to the development of potential therapies targeting immune-related diseases.
Product Title:
FITC Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:
AGEL0587
Size:
25µg, 100µg
Clone No:
2.4G2
Synonyms:
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
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