Biotin Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0051)

(No reviews yet) Write a Review
SKU:
AGEL0051
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
2.4G2
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Biotin Anti-Mouse CD16/32 Antibody [2.4G2]

The Biotin-Conjugated Mouse CD16/32 Monoclonal Antibody (2.4G2) is designed for advanced research involving CD16 and CD32, critical cell surface molecules involved in immune response regulation. These receptors play pivotal roles in processes such as antibody-dependent cellular cytotoxicity and phagocytosis. This monoclonal antibody, produced in mice, is highly reactive with mouse samples and validated for use in flow cytometry applications. The biotin conjugation enhances detection and quantification through various biotin-avidin/streptavidin-based assay systems, ensuring precise and reliable results.CD16 (FcγRIII) and CD32 (FcγRII) are receptors for the Fc region of immunoglobulins and are key players in immune complex-mediated responses, including inflammation and activation of immune cells. The Biotin-Conjugated Mouse CD16/32 Monoclonal Antibody (2.

4G2) is an invaluable tool for researchers studying immune mechanisms, autoimmune disorders, and cancer immunotherapy. Additionally, its ability to block Fc receptor binding sites makes it indispensable for experiments requiring Fc receptor blockade to prevent non-specific binding.Understanding the activity and regulation of CD16 and CD32 is crucial for developing targeted therapies that manipulate immune functions. By enabling accurate and sensitive detection of CD16/32, this antibody supports comprehensive studies of immune response pathways, contributing to the advancement of therapeutic strategies for autoimmune diseases, chronic inflammatory conditions, and cancer. This antibody is essential for advancing research in immunology and immune-related diseases.

Product Title:Biotin Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:AGEL0051
Size:25µg, 100µg
Clone No:2.4G2
Synonyms:CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Biotin Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P08508 P08101
Gene ID:14130,14131
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

0 Reviews

View AllClose

Related Products