The Mouse CD16/32 Monoclonal Antibody (APC conjugated, 2.4G2) is a powerful tool for researchers investigating the immune system and related processes. This highly specific antibody is designed for use in flow cytometry applications, allowing for the precise identification and analysis of CD16 and CD32 proteins on mouse cells.CD16 and CD32 are important cell surface receptors involved in immune responses, particularly in processes like phagocytosis and antibody-dependent cell-mediated cytotoxicity (ADCC). The APC conjugation of this monoclonal antibody enables easy visualization and quantification of CD16 and CD32 expression levels on various immune cell populations, providing valuable insights into their functions.
By using the Mouse CD16/32 Monoclonal Antibody (APC conjugated, 2.4G2), researchers can delve into the intricate mechanisms of immune regulation, inflammation, and host defense in mouse models. This antibody opens doors to a deeper understanding of immune cell interactions and responses, making it an essential tool for immunologists, cell biologists, and researchers exploring areas such as infectious diseases, autoimmune disorders, and immunotherapy.With its specificity, sensitivity, and validation for flow cytometry applications, this antibody empowers researchers to uncover new discoveries and advance knowledge in the field of immunology.
Product Title:
APC Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:
AGEL0579
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
2.4G2
Synonyms:
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
![APC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0579)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/608x608/products/121354/119534/apc-anti-mouse-cd1632-antibody-2.4g2-agel0579__52169__75930.1732014046.jpg?c=1 "APC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0579)")
![APC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0579)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/1280x1280/products/121354/119534/apc-anti-mouse-cd1632-antibody-2.4g2-agel0579__52169__75930.1732014046.jpg?c=1&imbypass=on "APC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0579)")
![APC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0589)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/121363/119543/apc-anti-mouse-cd1632-antibody-2.4g2-agel0589__55404__01459.1732014051.jpg?c=1 "APC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0589)")
![Purified Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0050)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120464/118644/AGEL0050__19944__06687.1732013157.jpg?c=1 "Purified Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0050)")
![Biotin Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0051)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120465/118645/biotin-anti-mouse-cd1632-antibody-2.4g2-agel0051__56359__89970.1732013158.jpg?c=1 "Biotin Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0051)")
![FITC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0577)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/121352/119532/fitc-anti-mouse-cd1632-antibody-2.4g2-agel0577__56015__45143.1732014046.jpg?c=1 "FITC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0577)")
![FITC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0587)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/121361/119541/fitc-anti-mouse-cd1632-antibody-2.4g2-agel0587__32112__77621.1732014051.jpg?c=1 "FITC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0587)")